UMIN ID: UMIN000001228
Registered date:02/07/2008
Neuroimaging study for late-life depression
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | late-life depression |
| Date of first enrollment | 2008/07/01 |
| Target sample size | 60 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | PET, MRI, Neuropsychology PET, MRI, Neuropsychology |
Outcome(s)
| Primary Outcome | Findings of the comparison between depression patients and age- and gender-matched normal controls with regard to the following factors: PET study (serotonin-transporter binding, amyloid deposition, and glucose metabolism) Structural MRI Neuropsychology |
|---|---|
| Secondary Outcome | Relationships between clinical symptoms or disease course and neuroimaging or neuropsychological tests |
Key inclusion & exclusion criteria
| Age minimum | 60years-old |
|---|---|
| Age maximum | 84years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Exclusion criteria for patients 1) Serious suicidal ideation or behavior 2) Mini-mental state examination score at screening, <=23 points 3) Co-morbid other psychiatric disorders including drug dependence 4) Existence of brain organic disease, including current or past history of cerebrovascular disease, Parkinson's disease, and other related disorders 5) Existence of serious medical illnesses 6) Subjects who are judged by researchers as not suitable for participation in the study |
Related Information
| Primary Sponsor | National Institute of Radiological Sciences |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Ministry of Health, Labour and Welfare |
| Secondary ID(s) |
Contact
| public contact | |
| Name | |
| Address | Japan |
| Telephone | |
| Affiliation | National Institute of Radiological Sciences Molecular Imaging Center |
| scientific contact | |
| Name | Harumasa Takano, MD, PhD |
| Address | Anagawa 4-9-1, Inage-ku, Chiba City, Chiba 263-8555, Japan Japan |
| Telephone | |
| Affiliation | National Institute of Radiological Sciences Molecular Imaging Center |