UMIN ID: UMIN000001197
Registered date:01/07/2008
Randomized control trial of primary eradication therapies of Helicobacter pylori
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | Gastroduodenal ulcer infected by Helicobacter pylori |
| Date of first enrollment | 2007/10/01 |
| Target sample size | 240 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | rabeprazole 10mg bid, amoxicillin 750mg bid and clarithromycin 200mg bid lansoprazole 30mg bid, amoxicillin 750mg bid and clarithromycin 200mg bid |
Outcome(s)
| Primary Outcome | Assessment of the Helicobacter pylori eradication on the bassis of the urea breath test result |
|---|---|
| Secondary Outcome | Influence of the clarithromycin resistance of Helicobacter pylori and the CYP2C19 genotype of the host for the eradication thrapies |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1)Pregnant females 2)Lacting woman 3)Patients who has past history of allergy for the drugs used in this study 4)Patients who has coexisting severe disease 5)Patient whom examination doctor judged improper as testee |
Related Information
| Primary Sponsor | University of Tokyo Hospital Department of Gastroenterology |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | None |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Masao Akanuma |
| Address | Japan |
| Telephone | |
| makanuma@qd6.so-net.ne.jp | |
| Affiliation | The University of Tokyo Hospital Department of Gastroenterology |
| scientific contact | |
| Name | Masao Akanuma |
| Address | 7-3-1 Hongo, Bunkyo-ku, Tokyo Japan |
| Telephone | 03-3815-5411(33070) |
| Affiliation | The University of Tokyo Hospital Department of Gastroenterology |