Metabolism of Iron and Erythropoiesis-stimulating agents (ESA) in chronic kidney disease (CKD)

UMIN ID: UMIN000001121

Registered date:22/04/2008

Basic Information

• Recruitment status: Complete: follow-up continuing
• Health condition(s) or Problem(s) studied: CKD (non-dialysis, dialysis)
• Date of first enrollment: 2008/05/01
• Target sample size: 40
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Treatment with long-acting ESA; dose of ESA and iron were changed by Hb concentration (target 10-11 g/dl).
Treatment with traditional ESA; dose of ESA and iron were changed by Hb concentration (target 10-11 g/dl).

Outcome(s)

• Primary Outcome: metabolism of iron, oxidative stress, and factors of atherogenesis

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: 90years-old
• Gender: Male and Female
• Exclude criteria: 1)Malignancy 2)Malnutrition 3)Active inflammatory or infectious disease 4)Uncontrollable diabetes mellitus 5)Abdominal ascites or pleural effusion 6)Pregnancy 7)Inappropriate for this study judged by the physicians

Related Information

• Primary Sponsor: Hyogo College of Medicine
• Source(s) of Monetary Support: Hyogo College of Medicine