NIPH Clinical Trials Search

UMIN ID: UMIN000001116

Registered date:09/04/2008

JPLT2 protocol (CITA and ITEC regimen)for the pediatric liver tumor in Japan

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedhepatoblastoma hepatocellular carcinoma
Date of first enrollment2000/04/01
Target sample size220
Countries of recruitmentJapan
Study typeObservational


Primary OutcomeEffect of tumor reduction Improvement of event-free and overall survivals Safety
Secondary OutcomePancytopenia Digestive organ dysfunction Late complications (cardiac dysfunction, growth disorder, hearing disorder)

Key inclusion & exclusion criteria

Age minimum1days-old
Age maximum15years-old
GenderMale and Female
Include criteria
Exclude criteriaNote that, even if an intrahepatic tumor, the benign liver tumor, hepatocellular carcinoma, and metastatic liver tumors should be excluded.

Related Information


public contact
Name Sho Kurihara
Address 1-2-3,Kasumi,Minami-ku,Hiroshima Japan 734-8551
Telephone 082-257-5216
Affiliation Hiroshima university hospital Pediatric Surgery
scientific contact
Name Hiyama Eiso
Address 1-2-3,Kasumi,Minami-ku,Hiroshima Japan
Telephone 082-257-5951
Affiliation Hiroshima University Natural Science Center for Basic Research and Development