UMIN ID: UMIN000001085
Registered date:20/03/2008
Effect of insulin sensitizer treatment on carotid arterial elasticity
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | type2 diabetes |
| Date of first enrollment | 2007/12/01 |
| Target sample size | 50 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Pioglitazone 15mg daily Metformin 750mg daily |
Outcome(s)
| Primary Outcome | change of carotid arterial elasticity |
|---|---|
| Secondary Outcome | changes of serum markers of atheroscrerosis,pulse wave velocity and carotid intima-media thickness |
Key inclusion & exclusion criteria
| Age minimum | 35years-old |
|---|---|
| Age maximum | 70years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | severe renal dysfunction severe liver dysfunction heart failure history of lactic acidosis severe retinopathy severe vascular disease with urgent treatment HbA1c over 9% blood pressure over 180/100 mmHg |
Related Information
| Primary Sponsor | Tohoku University Graduate School of Medicine |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Tohoku University Graduate School of Medicine,Division of Molecular Metabolism and Diabetes |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Yasushi Ishigaki |
| Address | Seiryou,1-1,Aobaku,Sendai Japan |
| Telephone | 022-717-7611 |
| yishigaki@mail.tains.tohoku.ac.jp | |
| Affiliation | Tohoku University Graduate School of Medicine Division of Molecular Metabolism and Diabetes |
| scientific contact | |
| Name | Yoshitomo Oka |
| Address | Seiryou,1-1,Aobaku,Sendai Japan |
| Telephone | 022-717-7611 |
| Affiliation | Tohoku University Graduate School of Medicine Division of Molecular Metabolism and Diabetes |