NIPH Clinical Trials Search

UMIN ID: UMIN000001079

Registered date:01/04/2008

Granulocyte colony-stimulating factor-mediated neuroprotection for acute spinal cord injury

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedacute spinal cord injury
Date of first enrollment2008/04/01
Target sample size10
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)administration of granulocyte colony-stimulating factor


Primary OutcomeTo clarify the safety of granulocyte colony-stimulating factor for acute spinal cord injury
Secondary Outcomedegree of sensory or motor paralysis, functional impairment coused by the paralysis, MRI imaging of injured spinal cord

Key inclusion & exclusion criteria

Age minimum16years-old
Age maximum70years-old
GenderMale and Female
Include criteria
Exclude criteriaAllergy for G-CSF. A patient with the past of a hematopoietic system malignant disease, any malignant disease within 5 years, angina, myocardial infarction, thrombosis, splenpmegary, consciousness disorder or pregnancy. A patient with the past which has concurred with the diseases of the nervous system which can have on neurological-symptoms evaluations, such as cerebral infarction. In addition, the patient whom the examination responsibility (assignment) doctor judged to be unsuitable as a subject.

Related Information


public contact
Address Japan
Telephone 043-226-2117
Affiliation Chiba University, Graduate School of Medicine Department of Orthopaedic Surgery
scientific contact
Name Masashi Yamazaki
Address 1-8-1 Inohana, Chuo-ku, Chiba, Japan Japan
Telephone 043-226-2117
Affiliation Chiba University Hospital Department of Orthopaedic Surgery