Granulocyte colony-stimulating factor-mediated neuroprotection for acute spinal cord injury

UMIN ID: UMIN000001079

Registered date:01/04/2008

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: acute spinal cord injury
• Date of first enrollment: 2008/04/01
• Target sample size: 10
• Countries of recruitment: Japan
• Study type: Interventional
• Intervention(s): administration of granulocyte colony-stimulating factor

Outcome(s)

• Primary Outcome: To clarify the safety of granulocyte colony-stimulating factor for acute spinal cord injury
• Secondary Outcome: degree of sensory or motor paralysis, functional impairment coused by the paralysis, MRI imaging of injured spinal cord

Key inclusion & exclusion criteria

• Age minimum: 16years-old
• Age maximum: 70years-old
• Gender: Male and Female
• Exclude criteria: Allergy for G-CSF. A patient with the past of a hematopoietic system malignant disease, any malignant disease within 5 years, angina, myocardial infarction, thrombosis, splenpmegary, consciousness disorder or pregnancy. A patient with the past which has concurred with the diseases of the nervous system which can have on neurological-symptoms evaluations, such as cerebral infarction. In addition, the patient whom the examination responsibility (assignment) doctor judged to be unsuitable as a subject.

Related Information

• Primary Sponsor: Chiba University Hospital
• Source(s) of Monetary Support: None