Randomized Trial of Icodextrin and Glucose Dialysate in CAPD Patients with Diabetic Nephropathy

UMIN ID: UMIN000001040

Registered date:18/02/2008

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: Patients with end-stage renal disease caused by diabetic nephropathy, who have 10 years history of diabetes and diabetic retinopathy.
• Date of first enrollment: 2005/05/26
• Target sample size: 100
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Group 1:The group treated with glucose dialysis solution.
Group2:The group treated with Icodextrin dialysis solution and glucose dialysis solution.

Outcome(s)

• Primary Outcome: Drop out rate of CAPD therapy
• Secondary Outcome: Residual renal function

Key inclusion & exclusion criteria

• Age minimum: 18years-old
• Age maximum: 80years-old
• Gender: Male and Female
• Exclude criteria: 1. Urine volume less than 400 ml. 2. Urinaly tract obstruction caused by renal stones, tumors, trauma, and neuronal bladder) 3. Pregnancy 4. Patients treated with PD, HD, or transplantaion for more than 3 months. 5. Patients, who are younger than 18 years and older than 80 yeras. 6. Contraindication (allergic) to Extraneal.

Related Information

• Primary Sponsor: Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine
• Source(s) of Monetary Support: Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine