Primary Hyperaldosteronism in Japan

UMIN ID: UMIN000000998

Registered date:01/02/2008

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: hypertension
• Date of first enrollment: 2005/06/01
• Target sample size: 3500
• Countries of recruitment: Japan
• Study type: Observational

Outcome(s)

• Primary Outcome: Prevalence of primary aldosteronism in patients with hypertension in Japan
• Secondary Outcome: Secondary outcomes are to establish the importance of investigating the cause of hypertension in clinical practice and to spread the standard medical practice specific to the cause of hypertension.

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: 75years-old
• Gender: Male and Female
• Exclude criteria: 1)pregnant patients 2)patients taking diuretics or aldosterone antagonist 3)patients with the following diseases: (1)secondary hypertension (renal hypertension,renovascular hypertension, primary aldosteronism, Cushing's syndrome, pheochromocytoma, iatrogenic diseases etc) (2)patients whom the attending doctors decides not suitable for the entry because of the unstable stage of the following complications: coronary diseases, arrhythmia, severe valvular diseases, cerebrovascular diseases, acute and chronic renal failure (serum Cr higher than 3mg/dl), acute and chronic liver diseases (3)orthostatic hypotension 4) Patients whom the attending doctor decides not suitable for the entry of the study.

Related Information

• Primary Sponsor: National Hospital Organization
• Secondary Sponsor: Cooperative research group for PHAS-J Study of National Hospital Organization
• Source(s) of Monetary Support: National Hospital Organization