NIPH Clinical Trials Search

UMIN ID: UMIN000000970

Registered date:01/02/2008

Analysis of risk factors and prognostic factors included histological status of underlying liver disease of patients undergoing curative resection or radiofrequency ablation of hepatocellular carcinoma; May hepatic steatosis correlate with the postoperative recurrence of hepatocellular carcinoma?

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedPatients with Hepatocellular carcinoma(HCC) after curative treatment
Date of first enrollment2004/07/01
Target sample size400
Countries of recruitmentJapan
Study typeObservational


Primary OutcomeThe cumulative tumor recurrence rate in patients with HCC
Secondary OutcomeCumulative survival rate in patients with HCC. Risk factors of recurrence of HCC and prognostic factors(these histological findings such as liver steatosis, liver fibrosis, and inflammation, Cancer Stage, Child-Pugh,and laboratory data, etc.)

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximumNot applicable
GenderMale and Female
Include criteria
Exclude criteriaa)Recurred HCC b)uncontrolled other malignancies c)ruptured HCC d)Operation-related death e)Judged to be inadequate case of this clinical study for other reasons by doctors

Related Information


public contact
Address Japan
Affiliation National Hospital Organization IwakuniClinical Center Internal Medicine
scientific contact
Name Yoshitaka Takuma
Address 2-5-1 Kuroiso-cho, Iwakuni, Yamaguchi, Japan Japan
Affiliation National Hospital Organization Iwakuni Clinical Center Internal Medicine