NIPH Clinical Trials Search

UMIN ID: UMIN000000961

Registered date:07/01/2008

Feasibility study of neoadjuvant chemotheray mFOLFOX6 for resectable liver metastases of colorectal cancers

Basic Information

Recruitment status
Health condition(s) or Problem(s) studiedcolorectal cancers
Date of first enrollment2008/01/01
Target sample size27
Countries of recruitmentJapan
Study typeInterventional


Primary OutcomeCurative resection rates of liver metastases
Secondary Outcome

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximum80years-old
GenderMale and Female
Include criteria
Exclude criteriaExcluded are cases with conditions as below: 1) Peritoneal or pleural fluid retention to be drainaged. 2) Multiple malignancies to be treated. 3) Peripheral neural disturbances. 4) Active infectious diseases. 5) Severe watery diarrhea. 6) Mental disturbances. 7) Treatment history of continuous, oral or intravenous steroid therapy. 8) Previous history of ischemic heart diseases. 9) Coexistent severe diseases including pulmonary fibrosis, interstitial pneumonia, ileus, uncontrollable diabetes, cardiac dysfunction, hepatic failure, or renal failure. 10) Pregnant. 11) Previous history of severe drug-induced allergy.

Related Information


public contact
Address Japan
Telephone 075-751-3227
Affiliation Kyoto Univ Hospital Surgery
scientific contact
Name Satoshi Nagayama
Address 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto City Japan
Affiliation Kyoto Univ Hospital Surgery