Short Treatment with the Angiotensin Receptor Blocker Candesartan Surveyed by Telemedicine

UMIN ID: UMIN000000941

Registered date:01/04/2008

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: Hypertension
• Date of first enrollment: 2008/04/01
• Target sample size: 220
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Candesartan 4-12 mg po qd
Nifedipine XL 10-40 mg po qd

Outcome(s)

• Primary Outcome: Antihypertensive drug withdrawal success rates
• Secondary Outcome: 1. Median duration of drug withdrawal 2. Changes in home and office BP values after drug withdrawal

Key inclusion & exclusion criteria

• Age minimum: 30years-old
• Age maximum: 59years-old
• Gender: Male and Female
• Exclude criteria: Patients satisfying any one of the following criteria will be excluded from the study: 1.Secondary hypertension 2.Diabetes mellitus (HbA1c values of 6.5% or greater) 3.Renal dysfunction (serum creatinine values of 2 mg/dl or greater) 4.Patients with a history of cardiovascular disease (stroke, transient ischemic attack, coronary heart disease, heart failure) 5.Patients with severe liver dysfunction 6.Patients with malignancies 7.Pregnant patients, or patients intending to be pregnant 8.Other patients judged to be inappropriate by the attending physician

Related Information

• Primary Sponsor: Department of Internal Medicine, School of Medicine, Keio University
• Source(s) of Monetary Support: Japan Vascular Disease Research Foundation