Effects of traditional Chinese medicine for chorea in the Huntington's disease.

UMIN ID: UMIN000000909

Registered date:16/05/2008

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: Huntington's disease
• Date of first enrollment: 2007/10/01
• Target sample size: 4
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Step1 To take Chai hu jia long gu mu li tang 56 days Step2 Wash out 28 days Step3 To take Yigan San 56 days
Step1 To take Yigan San 56 days Step2 Wash out 28 days Step3 To take Chai hu jia long gu mu li tang 56 days

Outcome(s)

• Primary Outcome: Unified Huntington's Disease Rating Scale (UHDRS)
• Secondary Outcome: Cognitive function, ADL, Use of rescue drug, toralance

Key inclusion & exclusion criteria

• Age minimum: 40years-old
• Age maximum: 80years-old
• Gender: Male and Female
• Exclude criteria: 1.with any malignancy 2.with severe heart disease, liver disease, blood disease, respiratory disease and any other severe diseases influenced on the patients states 3.With any neurodegenerating diseases other than Huntington's disease 4.Alcohol abuse, drug abuse, metabolic toxicity, chronic inflammatory diseases 5.Who can not take herbal medicine per os. 6.Who are perscribed any antipsychotics newly in the observation period. 7. Others who are judged as inadequate by attending doctors.

Related Information

• Primary Sponsor: Yonezawa National Hospital
• Source(s) of Monetary Support: Yonezawa National Hospital.