NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
UMIN ID: UMIN000000882

Registered date:01/12/2007

Treatment effects of antithrombin in septic patients with disseminated intravascular coagulation (DIC).

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedSepsis associated with disseminated intravascular coagulation (DIC).
Date of first enrollment2008/01/01
Target sample size200
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Antithrombin III, Three days, 30 IU/kg, One administration/day No treatment.

Outcome(s)

Primary OutcomeImprovement of DIC score, coagulation and fibrinolytic markers on the four days after antithrombin treatment.
Secondary OutcomeTwenty-eight day mortality

Key inclusion & exclusion criteria

Age minimum15years-old
Age maximumNot applicable
GenderMale and Female
Include criteria
Exclude criteria1) < Fifteen years of age, 2) Hematopoetic malignancy, 3) Comcomitant treatment with cartinostatics or irradiation, 4) Liver cirrhosis classified as Child-Pugh C, 5) Early phase of trauma and burn injury.

Related Information

Contact

public contact
Name Satoshi Gando
Address N17 W5, Kita-ku, Sapporo Japan
Telephone 011-706-7377
E-mail gando@med.hokudai.ac.jp
Affiliation Hokkaido University Graduate School of Medicine Acute and Critical Care Medicine
scientific contact
Name Satoshi Gando
Address N17 W5, Kita-ku, Sapporo Japan
Telephone 011-706-7377
E-mail
Affiliation Hokkaido University Graduate School of Medicine Acute and Critical Care Medicine