UMIN ID: UMIN000000871
Registered date:01/11/2007
Prospective Observational Survey on the Long-Term Effects of the LDL-Apheresis on the Drug Resistant Nephrotic Syndrome
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Refractory (drug resistant) nephrotic syndrome |
| Date of first enrollment | 2007/01/01 |
| Target sample size | 200 |
| Countries of recruitment | Japan |
| Study type | Observational |
| Intervention(s) |
Outcome(s)
| Primary Outcome | Rate of clinical improvement (total number of the complete remission and the type I incomplete remission) |
|---|---|
| Secondary Outcome | Correlation between the rate of clinical improvement and the following factors which could influence the therapeutic effect 1. stage of nephritic syndrome 2. age 3. severity of renal lesion 4. severity of glomerulosclerosis, degree of tubular damage, selectivity index, etc. 5. TAT (blood coagulation marker) level 6. period between the onset of nephritic syndrome and the application of LDL-application 7. frequency of LDL-apheresis 8. dose of steroids used in combination with LDL-apheresis 9. presence or absence of steroid pulse during LDL-apheresis |
Key inclusion & exclusion criteria
| Age minimum | Not applicable |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | not applicable |
Related Information
| Primary Sponsor | the Japanese Society of Kidney and Lipids Research |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | The Kidney Foundation, Japan |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Eri Muso |
| Address | 2-4-20 Ohgimachi, Kita-ku, Osaka 530-8480, Japan Japan |
| Telephone | 06-6312-8824 |
| polaris2001polaris@yahoo.co.jp | |
| Affiliation | Kitano Hospital, The Tazuke Kofukai Medical Research Institute Division of Nephrology and Dialysis |
| scientific contact | |
| Name | Takao Saito |
| Address | 7-45-1 Nakakuma, Jonan-ku, Fukuoka 814-0180, Japan Japan |
| Telephone | 092-801-1011 |
| Affiliation | Fukuoka University School of Medicine Division of Nephrology and Rheumatology |