NIPH Clinical Trials Search

UMIN ID: UMIN000000871

Registered date:01/11/2007

Prospective Observational Survey on the Long-Term Effects of the LDL-Apheresis on the Drug Resistant Nephrotic Syndrome

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedRefractory (drug resistant) nephrotic syndrome
Date of first enrollment2007/01/01
Target sample size200
Countries of recruitmentJapan
Study typeObservational


Primary OutcomeRate of clinical improvement (total number of the complete remission and the type I incomplete remission)
Secondary OutcomeCorrelation between the rate of clinical improvement and the following factors which could influence the therapeutic effect 1. stage of nephritic syndrome 2. age 3. severity of renal lesion 4. severity of glomerulosclerosis, degree of tubular damage, selectivity index, etc. 5. TAT (blood coagulation marker) level 6. period between the onset of nephritic syndrome and the application of LDL-application 7. frequency of LDL-apheresis 8. dose of steroids used in combination with LDL-apheresis 9. presence or absence of steroid pulse during LDL-apheresis

Key inclusion & exclusion criteria

Age minimumNot applicable
Age maximumNot applicable
GenderMale and Female
Include criteria
Exclude criterianot applicable

Related Information


public contact
Name Eri Muso
Address 2-4-20 Ohgimachi, Kita-ku, Osaka 530-8480, Japan Japan
Telephone 06-6312-8824
Affiliation Kitano Hospital, The Tazuke Kofukai Medical Research Institute Division of Nephrology and Dialysis
scientific contact
Name Takao Saito
Address 7-45-1 Nakakuma, Jonan-ku, Fukuoka 814-0180, Japan Japan
Telephone 092-801-1011
Affiliation Fukuoka University School of Medicine Division of Nephrology and Rheumatology