UMIN ID: UMIN000000854
Registered date:18/10/2007
Clinical study on efficacy and safety of autologous gamma/delta T cell transfer therapy after pulmonary metastasectomy of colorectal cancer
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | lung metastasis of colorectal cancer |
| Date of first enrollment | 2007/10/01 |
| Target sample size | 20 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Gannma/delta T cells are injected on day0, day7, day14, day21, day28, day35, day42, day49. |
Outcome(s)
| Primary Outcome | Relapse rate(1 and 2 years) |
|---|---|
| Secondary Outcome | Relapse free survival Overall survival Survival rate(1 and 2 years) Response of tumor-related markers Immunological response Safety |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Patients who have - Pulmonary fibrosis or interstitial pneumonia, or their history, or predisposition to them; - Active enteritis, autoimmune diseases, and/or infections - Double cancer; - Other serious complications; - Continuous systemic administration of steroids. |
Related Information
| Primary Sponsor | University of Tokyo, Graduate School of Medicine |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Medinet Co.,Ltd. |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Kazuhiro Kakimi |
| Address | 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan Japan |
| Telephone | 03-5805-3161 |
| immunotherapy-admin@umin.ac.jp | |
| Affiliation | University of Tokyo, Graduate School of Medicine Department of Immunotherapeutics |
| scientific contact | |
| Name | Jun Nakajima |
| Address | 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan Japan |
| Telephone | 03-3815-5411 |
| Affiliation | University of Tokyo, Graduate School of Medicine Department of Cardiothoracic surgery |