NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
UMIN ID: UMIN000000845

Registered date:07/10/2007

Intra-arterial injection of donor mesenchymal stromal cells for treating refractory acute Graft-vs-Host disease after hemopoietic stem cell transplantation

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedrefractory acute GVHD
Date of first enrollment2006/04/01
Target sample size8
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Intra-arterial administration of donor-derived mesenchymal stromal cells

Outcome(s)

Primary OutcomeClinical response at 2 weeks after MSC therapy
Secondary OutcomeClinical response at 4 weeks after MSC therapy Overall survival at 4 weeks after MSC therapy

Key inclusion & exclusion criteria

Age minimum15years-old
Age maximumNot applicable
GenderMale and Female
Include criteria
Exclude criteria1.Positive for HIV Ab 2.Uncontrollable infection such as mucor, EBV-LPD, Gancyclovir-refractory CMV, measles. 3.severe psychiatric disorder

Related Information

Contact

public contact
Name Nobuyoshi Arima
Address 2-4-20 Ohgimachi, Kita-ku, Osaka, JAPAN Japan
Telephone
E-mail n-arima@kitano-ho.or.jp
Affiliation The Tazuke Kofukai Medical Research Institute Kitano Hospital Department of Hematology
scientific contact
Name Nobuyoshi Arima
Address 2-4-20 Ohgimachi, Kita-ku, Osaka, JAPAN Japan
Telephone
E-mail
Affiliation The Tazuke Kofukai Medical Research Institute Kitano Hospital Department of Hematology