Study about efficacy and tolerance of acetate free biofiltration (AFB) in dialysis patients:clinical significance of acetate free and acidisis correction.(NABI study:Nagoya acetate free biofiltration study)

UMIN ID: UMIN000000827

Registered date:28/09/2007

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: Dysdialysis syndrome
• Date of first enrollment: 2007/08/01
• Target sample size: 20
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

1)A:from HDF to AFB
2) B:from AFB to HDF

Outcome(s)

• Primary Outcome: Ffficacy (1)circulation stability (Blood pressure,PWV) (2)improvement of QOL (3)clinical significance of acidosis correction (Ca and Pi metabolism) (4)clinical significance of Acetate free (endthelial injury,inflammation)

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: (1)blood disease, malignant disorder, severe liver disorder (2) uses steroid, immunosuppression agent (3) 20 years or older. (4) participating in another clinical trial for 12 weeks or longer. (5) pregnant, during the nursing, possibly pregnant and having the hope of child bearing. (6)judged inappropriate as study subject by the investigator.

Related Information

• Primary Sponsor: Nagoya University
• Source(s) of Monetary Support: Nagoya University, Nephrology