UMIN ID: UMIN000000790
Registered date:07/11/2007
The Heart Institute of Japan Candesartan Randomized trial for Evaluation in Coronary Artery Disease
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Coronary artery disease |
| Date of first enrollment | 2001/06/01 |
| Target sample size | 2030 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Candesartan-based therapy without any angiotensin-converting enzyme inhibitors Non-ARB based standard therapy |
Outcome(s)
| Primary Outcome | The primary endpoint of the present study was the time to the first major adverse cardiovascular events. |
|---|---|
| Secondary Outcome | The major secondary endpoints included the incidence of coronary revascularization and new-onset diabetes. |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 80years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Patients with socondary hypertension hypertrophic obstructive cardiomyopathy Acute myocardial infarction (withih 7 days) cerebrovascular disease within 3 months serum Creatinine >=2.0mg/dl hyperkalemia |
Related Information
| Primary Sponsor | HIJC Study group |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | The Japan Research Promotion Society for Cardiovascular Diseases, Tokyo, Japan. |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Hiroshi Ogawa |
| Address | 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan Japan |
| Telephone | 03-3353-8111 |
| mogawa@hij.twmu.ac.jp | |
| Affiliation | The Heart Institute of Japan, Tokyo Women's Medical University Cardiology |
| scientific contact | |
| Name | Hiroshi Kasanuki |
| Address | 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan Japan |
| Telephone | 03-3353-8111 |
| Affiliation | The Heart Institute of Japan, Tokyo Women's Medical University Cardiology |