UMIN ID: UMIN000000765
Registered date:13/07/2007
BEDTIME ADMINISTRATION OF LONG-ACTING ANTIHYPERTENSIVE DRUGS RESTORES NORMAL NOCTURNAL BLOOD PRESSURE FALL IN NON-DIPPERS WITH ESSENTIAL HYPERTENSION
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Essential hypertension |
| Date of first enrollment | 2003/05/01 |
| Target sample size | 100 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | We studied Japanese adult patients with essential hypertension who had been receiving long-acting antihypertensive drugs once daily in the morning and changed medication time to bedtime in non-dippers after 24-hour ambulatory blood pressure monitoring. |
Outcome(s)
| Primary Outcome | the office and 24-hour ambulatory blood pressure, and the percentages of nocturnal decline in blood pressure |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Patients with diabetes, renal dysfunction (serum creatinine>1.2 mg/dL), or a history of cardiovascular diseases were excluded |
Related Information
| Primary Sponsor | Tsuchiura Kyodo General Hospital |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | none |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Atsushi Takeda |
| Address | 2526-1, Nishimura, Kutsukake, Bando-shi, Ibaraki-ken, 306-0515, Japan Japan |
| Telephone | 0297-30-3311 |
| atakeda@midorino.com | |
| Affiliation | Midorino Clinic Director |
| scientific contact | |
| Name | Atsushi Takeda |
| Address | 11-7, Manabeshinmachi, Tsuchiura-shi, Ibaraki-ken, Japan Japan |
| Telephone | 029-823-3111 |
| Affiliation | Tsuchiura Kyodo General Hospital Kidney Center |