NIPH Clinical Trials Search

UMIN ID: UMIN000000750

Registered date:01/07/2007

Observational Registry:Gastrointestinal Complications developed during low-dose aspirin intake or atherothrombosis such as myocardial infarction and cerebral infarction-

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedCerebral infarction, TIA, angina, myocardial infarction, atrial fibrillation
Date of first enrollment2005/01/01
Target sample size1500
Countries of recruitmentJapan
Study typeObservational


Primary OutcomeFindings of ulcer, and erosion in upper GI under endoscopy
Secondary OutcomeEvent rate: GI hemorrhage and alternative LANZA score (stomach), Cerebral hemorrhage, Other systematic hemorrhage, cardiovascular death, nonfatal MI, nonfatal cerebrovascular infarction, TIA, Coronary angioplasty /STENT insertion, worsening of primary disease

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximum100years-old
GenderMale and Female
Include criteria
Exclude criteria1) Serious hepatic or renal disorder with treatment required, 2)Serious lung disorder with treatment required, 3)Pregnant, Possible pregnant, Pregnant desired, 4) Uncontrolled DM, 5)Cancer patient with treatment required, 6)Patient experienced surgery for esophagus, stomach, and duodenal disease, 7)Patient having hypersensitivity against aspirin or other salicylic acids, 8)Patient whom the investigator determined as inadequate

Related Information


public contact
Name Shinya Goto
Address 143 Shimokasuya, Isehara, Kanagawa 259-1143, Japan Japan
Telephone 0463-93-1121
Affiliation Tokai University School of Medicine Department of Medicine
scientific contact
Name Yasuo Ikeda
Address Shinanomachi 35 Shinjyuku-ku Tokyo Japan
Telephone 03-3353-1211
Affiliation Keio University School of Medicine Department of Medicine