NIPH Clinical Trials Search

UMIN ID: UMIN000000747

Registered date:01/09/2007

Prednisolone therapy of the first episode of idopatic nephrotic syndrome in children: A Multi-center randomized controlled trial

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedIdiopatic nephrotic syndrome in children
Date of first enrollment2007/09/01
Target sample size250
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)PSL for 2 months PSL for 6 months


Primary OutcomeTime to frequent relapse
Secondary Outcome

Key inclusion & exclusion criteria

Age minimum1years-old
Age maximum15years-old
GenderMale and Female
Include criteria
Exclude criteria1)Other renal nephrotic syndrome(IgA nephropathy) 2)Henoch-Schönlein nephritis, systemic lupus erythematosus 3)History of immunosuppressant administration. 4)Poorly controlled hypertension. 5)Renal dysfunction(creatinine clearance < 60 mL/min). 6)Active infectious disease. 7)Severe liver disfunction. 8)Pregnancy. 9)Judged inappropriate for this study by the physicians.

Related Information


public contact
Name Nakanishi
Address Japan
Telephone 073-441-0633
Affiliation Japanese Study Group of Kidney Disease in Children Department of Pediatrics, Wakayama Medical University
scientific contact
Name Norishige Yoshikawa
Address 811-1 Kimiidera Wakayama City Wakayama Japan
Telephone 073-441-0633
Affiliation Wakayama Medical University Department of Pediatrics