UMIN ID: UMIN000000729
Registered date:10/06/2007
Comprison of the renoprotecrive and the antihypertensive effects of Olmesartan vs Losartan + low dose diuretics in normoalbuminuric diabetic patients
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | diabetes |
| Date of first enrollment | 2007/04/01 |
| Target sample size | 30 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Olmesartan (20mg) Losartan (50mg) + hydrochlorothiazide (12.5mg) or trichlorothiazide (1mg) |
Outcome(s)
| Primary Outcome | 1. changes in urinary IgG, transferrin and ceruloplasmin excretions 2. blood pressure lowering effects. |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 80years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1. Past history of microalbuminuria, overt proteinuria or any kidney diseases 2. Pregnancy 3. Severe liver dysfunction 4. Cancer 5. Poor glycemic control (HbA1c > 10%) 6. Other reasons for exclusion |
Related Information
| Primary Sponsor | Akita Olmesartan renoprotection study group |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Self funding |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Takuma Narita |
| Address | Hondo 1-1-1, Akita, Japan Japan |
| Telephone | |
| Affiliation | Akita University School of Medicine Endocrinology, diabetes and geriatric medicine |
| scientific contact | |
| Name | Takuma Narita |
| Address | Hondo 1-1-1, Akita, Japan Japan |
| Telephone | 018-884-6040 |
| Affiliation | Akita University School of Medicine Endocrinology, diabetes and geriatric medicine |