UMIN ID: UMIN000000700
Registered date:02/05/2007
Target organ damage related gene evaluation using olmesartan in hypertensive patients with diabetes mellitus
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | Hypertension with diabetes mellitus |
| Date of first enrollment | 2007/01/01 |
| Target sample size | 200 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | administration of angiotensin receptor blockade (ARB:Olmesartan) |
Outcome(s)
| Primary Outcome | Gene polymorphisms related to to cardiovascular-renal protection by ARB in hypertensive patients with diabetes mellitus |
|---|---|
| Secondary Outcome | Gene polymorphisms related to to blood pressure reduction or glucose metabolism by ARB in hypertensive patients with diabetes mellitus |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 85years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Severe hypertensive patients, who have BP above 180/110mmHg Female patients with pregnancy or possibility of pregnancy Patients just after acute myocardial infarction or stroke within a month Inappriate patients for this study |
Related Information
| Primary Sponsor | National Cardiovascular Center |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Health Sciences of the National Institute of Biomedical Innovation of Japan |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Kei Kamide |
| Address | 5-7-1, Fjishirodai, Suita, Osaka 565-8565, Japan Japan |
| Telephone | 06-6833-5012 |
| kamide@hsp.ncvc.go.jp | |
| Affiliation | National Cardiovascular Center Division of Hypertension and Nephrology |
| scientific contact | |
| Name | Takayuki Morisaki |
| Address | 5-7-1, Fjishirodai, Suita, Osaka 565-8565, Japan Japan |
| Telephone | 06-6833-5012 |
| Affiliation | National Cardiovascular Center Research Institute |