UMIN ID: UMIN000000689
Registered date:31/03/2008
Effect of pioglitazone on renal function amelioration by measurement of cystatine C levels in the type 2 diabetic patients
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Diabetic nephropathy |
| Date of first enrollment | 2007/05/01 |
| Target sample size | 70 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | pioglitazone 15-30mg/day metformin 750mg/day |
Outcome(s)
| Primary Outcome | cystatine C, creatinine clearance, albumin extcretion rate, creatinine |
|---|---|
| Secondary Outcome | general biochemical tests, HOMA-R, fasting blood insulin, serum resistin, CRP, adiponectin, leptin levels |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 75years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1)The patient that it is already taken thiazolidinedione. 2)The patient with serious liver functional dysfunction. 3)Gravida or the patient with pregnant likelihood. 4)It is the patient with irritation for thiazolidinedione. |
Related Information
| Primary Sponsor | Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | NONE |
| Secondary ID(s) |
Contact
| public contact | |
| Name | EITARO NAKASHIMA |
| Address | 65 Tsurumai-cho, Showa-ku, Nagoya Japan |
| Telephone | 052-744-2142 |
| eitaro@med.nagoya-u.ac.jp | |
| Affiliation | Nagoya University Hospital Department of Endocrinology and Diabetes |
| scientific contact | |
| Name | EITARO NAKASHIMA |
| Address | 65 Tsurumai-cho, Showa-ku, Nagoya Japan |
| Telephone | 052-744-2142 |
| Affiliation | Nagoya University Graduate School of Medicine Department of Endocrinology and Diabetes |