UMIN ID: UMIN000000667
Registered date:01/11/2008
Effects of renal dysfunction and sleep apnea on ambulatory blood pressure profile, cardiovascular function, and glucose and lipid metabolism: cross-sectional and prognosis study.
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Hypertensionj |
| Date of first enrollment | 2005/04/01 |
| Target sample size | 500 |
| Countries of recruitment | Japan |
| Study type | Observational |
| Intervention(s) |
Outcome(s)
| Primary Outcome | 1) casual blood pressure 2) ambulatory blood pressure monitoring 3) sleep apnea test 4) renal function: creatinine clearance by Cockcroft-Gault formula 5) glucose metabolism: fasting blood glucose, fasting IRI, HOMA-IR 6) lipid metabolism: total cholesterol, LDL, HDL, TG, adiponectin 7) cardiac function: ANP, BNP, UCG 8) vascular function: ABI/BWV, carotid echogram 9) sympathetic nerve activity and renin-angiotensin system 10) inflammatory and oxidative markers: CRP, fibrinogen, MDA-LDL, AGE. |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | acute myocardial infarction, collagen disease, acute renal failure |
Related Information
| Primary Sponsor | Yokohama City University School of Medicine |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Department of Medical Science and Cardiorenal Medicine, Yokohama City University School of Medicine |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Kazukai Uchino |
| Address | 3-9 Fukuura, Kanazawa-ku Japan |
| Telephone | 045-787-2634 |
| uchinok@med.yokohama-cu.ac.jp | |
| Affiliation | Yokohama City University School of Medicine Department of Medical Science |
| scientific contact | |
| Name | Kouichi TAMURA |
| Address | 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, JAPAN Japan |
| Telephone | 045-787-2635 |
| tamukou@med.yokohama-cu.ac.jp | |
| Affiliation | Yokohama City University School of Medicine Department of Cardiorenal Medicine |