NIPH Clinical Trials Search

UMIN ID: UMIN000000657

Registered date:01/04/2007

Hypothyroidism in Hyperlipidemia in Japan

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedHyperlipidemia
Date of first enrollment2006/10/01
Target sample size1000
Countries of recruitmentJapan
Study typeObservational


Primary OutcomePrevalence of hypothyroidism and/or subclinical hypothyroidism in patients with hyperlipidemia
Secondary OutcomeEffects of thyroid hormone replacement on serum lipid levels

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximum80years-old
GenderMale and Female
Include criteria
Exclude criteria1) Patients with known thyroid hormone abnormalities 2) Patients with hyperlipidemia due to known diseases other than the thyroid diseases: nephrotic syndrome, primary biliary cirrhosis, obstructive jaundice, Cushing's syndrome, acromegaly, pheochromocytoma, medicine (diuretics, beta blockers, steroid hormones, contraceptives, cyclosporin), heavy alcohol drinker 3) Pregnancy 4) Patients under steroid hormone treatment 5) Unstable stage of the following diseases; coronary diseases, arrhythmias, valvular diseases, heart failure, cerebrovascular diseases, renal failure, diabetes mellitus with very poor control, neuro-muscular diseases, malignancy 6) Conditions when doctors assume inappropriate to enroll

Related Information


public contact
Name Mitsuhide Naruse
Address 1-1 Fukakusa-Mukaihatacho, Fushimiku,Kyoto, Japan Japan
Telephone 075-641-9164
Affiliation National Hospital Organization, Kyoto Medical Center Department of Endocrinology, Clinical Research Institute for Endocrine and Metabolic Diseases
scientific contact
Name Hironori Kimura
Address Nagasaki Prefecture, Ohmura City, Hisahara,2-1001-1 Japan
Telephone 0957-52-3121
Affiliation National Hospital Organization Nagasaki Medical Center Medicine