UMIN ID: UMIN000000656
Registered date:01/04/2007
Clinical trial of mesenchymal stem cell transplantation for severe heart failure
Basic Information
| Recruitment status | Complete: follow-up continuing |
|---|---|
| Health condition(s) or Problem(s) studied | Severe chronic heart failure |
| Date of first enrollment | 2003/11/01 |
| Target sample size | 20 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | 11/1/2003-5/31/2009 |
Outcome(s)
| Primary Outcome | Safety Ejection fraction |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 80years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1. Any evidence of cancer or active infectious disease 2. Presence of proliferative diabetic retinopathy 3. Renal failure or hepatic failure 4. Any evidence for abnormality in peripheral blood 5. History of PTCA or CABG in the 6 months prior to study entry 6. History of acute myocardial infarctioin, unstable angina or myocarditis in the 6 months prior to study entry 7. Not pregnant 8. Presence of embolism in the left ventricle 9. Presence of aortic valve stenosis or aortic artificial valve 10. Very severe hear failure patients who can not endure invasive examination such as catheterization and bone marrow aspiration |
Related Information
| Primary Sponsor | National Cardiovascular Center |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Ministry of Health, Labour and Welfare |
| Secondary ID(s) |
Contact
| public contact | |
| Name | |
| Address | Japan |
| Telephone | |
| Affiliation | National Cardiovascular Center Research Institute Department of Regenerative Medicine & Tissue Engineering |
| scientific contact | |
| Name | Noritoshi Nagaya |
| Address | 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan Japan |
| Telephone | 06-6833-5012 |
| Affiliation | National Cardiovascular Center Research Institute Department of Regenerative Medicine & Tissue Engineering |