NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
UMIN ID: UMIN000000623

Registered date:01/03/2007

Clinical examination about immunoadsorption therapy for dilated cardiomyopathy

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studieddilated cardiomyopathy
Date of first enrollment2007/03/01
Target sample size20
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)During 10-20 days for study period, 3-5 immunoadsorption therapies will be performed by IMMUSORBA TR (AsahiKasei Medical CO.), which plasma throughput is 2-2.5 liters, three hours per once.

Outcome(s)

Primary OutcomeChanges of body weight, 6 minutes walking test, cardio-thoracic ratio, echocardiographic parameters, left ventricular ejection fraction, and plasma BNP level after 3-5 immunoadsorption therapies (10-20days).
Secondary OutcomePresence of side effect during 3-5 immunoadsorption therapies (10-20days).

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximumNot applicable
GenderMale and Female
Include criteriaNYHA 3 or 4, Left ventricular ejection fraction less than 30%, more than 6 months of standard medical treatments.
Exclude criteriaOn ACE inhibitors, With known heart basal diseases, Acute myocarditis, Active infectious disease (including viral hepatitis), Neoplasm, Excess alcoholic damages on liver or heart, Pregnancy.

Related Information

Contact

public contact
Name Akiyasu Baba
Address 5-9-1 Shirokane Minato-ku, Tokyo Japan
Telephone 03-3444-6161
E-mail web-hospital@kitasato.or.jp
Affiliation Kitasato Institute Hospital Department of Cardiology
scientific contact
Name Makoto Akaishi
Address 5-9-1 Shirokane Minato-ku, Tokyo Japan
Telephone 03-3444-6161
E-mail
Affiliation Kitasato Institute Hospital Department of Cardiology