UMIN ID: UMIN000000489
Registered date:01/10/2006
Study of High dose Toremifene for metastatic breast cancer after failure of adjuvant therapy of Aromatase Inhibitor
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | First line therapy for recurrence or metastatic postmenopausal breast cancer |
| Date of first enrollment | 2005/08/01 |
| Target sample size | 40 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Toremifene 120mg/day for at least 12 weeks until disease progression. |
Outcome(s)
| Primary Outcome | Response Rate |
|---|---|
| Secondary Outcome | Clinical benefit, Progression-Free Survival, adverse events |
Key inclusion & exclusion criteria
| Age minimum | Not applicable |
|---|---|
| Age maximum | Not applicable |
| Gender | Female |
| Include criteria | |
| Exclude criteria | 1.brain metastasis 2.bilateral brest cancer 3.male breast cancer 4.severe allergy 5.severe complications |
Related Information
| Primary Sponsor | Nagoya University of School of Medicine Breast and Endocrine Surgery |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | none |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Masataka Sawaki |
| Address | 65 tsurumai-cho showa-ku Nagoya city Japan |
| Telephone | 052-744-2251 |
| sawapi@qc4.so-net.ne.jp | |
| Affiliation | Nagoya University of School of Medicine Breast and Endocrine Surgery |
| scientific contact | |
| Name | Tsuneo Imai |
| Address | 65 tsurumai-cho showa-ku Nagoya city Japan |
| Telephone | 052-744-2251 |
| m-sawaki@aichi-cc.jp | |
| Affiliation | Nagoya University of School of Medicine Breast and Endocrine Surgery |