Prevention traial of dementia using nonpharmacological interventions in Mild Cognitive Impairment (MCI) among the community-dwelling elderly

UMIN ID: C000000449

Registered date:15/07/2006

Basic Information

• Recruitment status: Complete: follow-up continuing
• Health condition(s) or Problem(s) studied: Mild Cognitive Impairment (MCI)
• Date of first enrollment: 2003/06/01
• Target sample size: 50
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Intervention group attend the occupational therapy and aerobic therapy once a week for three years.
Non-intervention group attend a dementia enlightenment lectuer once a year and live ordinary life.
Control group does not attend dementia prevention program at all and lives a conventional life.

Outcome(s)

• Primary Outcome: The subject is observed cognitive functions using "Five-Cog", a neuropsychological assessment comprised of five categories: memory, attention, verbal fluency, clock drawing test, and analogy. This examination is evaluated every one year.
• Secondary Outcome: Brain perfusion SPECT study, MMSE, CDR, WMS-R (logical memory I)

Key inclusion & exclusion criteria

• Age minimum: 65years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: 1.Patients of (1)Ischemic heart disease (2)Dementia 2.Persons with mental problems 3.Pregnant women 4.Persons who are not adequate for the research

Related Information

• Primary Sponsor: Fifth Department of Internal Medicine, School of Medicine, Fukuoka University
• Source(s) of Monetary Support: Research grants from the Ministry of Health, Labour and Welfare, Japan