UMIN ID: C000000435
Registered date:23/06/2006
Prospective comparative study of neurocognitive function after total arch replacement: intermittent pressure augmented or conventional retrograde cerebral perfusion
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | Patients undergoing total arch replacement |
| Date of first enrollment | 2006/06/01 |
| Target sample size | 40 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Intermittent pressure augmented retrograde cerebral perfusion Conventional retrograde cerebral perfusion |
Outcome(s)
| Primary Outcome | Neurocognitive function assessed by the revised Wechsler Adult Intelligence Scale |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 79years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1. Patients having a history of cerebrovascular disease 2. Patients requiring emergency operation 3. Patients undergoing total arch replacement via left thoracotomy 4. Patients requiring concomitant valve or coronary-bypass operation 5. Severe liver disease 6. Severe renal disease 7. Patients whom physician judges inappropriate to the study |
Related Information
| Primary Sponsor | Departments of Cardiothoracic Surgery, the University of Tokyo |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | none |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Takayuki Ono |
| Address | Japan |
| Telephone | |
| Affiliation | University of Tokyo Cardiothoracic Surgery |
| scientific contact | |
| Name | Shinichi Takamoto |
| Address | 7-3-1, Hongo, Bunkyo-Ku, Tokyo Japan |
| Telephone | |
| Affiliation | University of Tokyo Cardiothoracic Surgery |