NIPH Clinical Trials Search

UMIN ID: C000000396

Registered date:04/04/2006

Validation study of new febrile neutropenia guideline-Comparative study between oral levofloxacin and parenteral cefepime in low-risk patients with febrile neutropenia

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedFebrile neutropenia
Date of first enrollment2005/10/01
Target sample size200
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)CFPM 4g,1h-div, q12 LVFX 200mg, tid


Primary OutcomeTreatment efficacy at 7 days after antimicrobiral therapy
Secondary OutcomeAdverse events, treatment results in 3-5 days after the start of therapy, succes rate as an outpatient, survival, antibacterial effect

Key inclusion & exclusion criteria

Age minimum16years-old
Age maximumNot applicable
GenderMale and Female
Include criteria
Exclude criteriaPoor-risk acute leukemia patients Isolation of microorganism resistant to the study drugs Past history of allergy to beta-lactum or study drugs Pregnant or lactating woman Age of 15 years or younger Antimicrobial treatment within 3 months prior to the study entry Allegenic hematopoietic stem cell transplantation

Related Information


public contact
Name Kazuo Tamura
Address Japan
Affiliation Fukuoka University Depatment of Internal Medicine
scientific contact
Name Akihisa Kanamaru
Address 377-2 Ohno-Higashi, Osaka-Sayama, Osaka Japan
Affiliation Kinki University Department of Hematology