Comparison of efficacy and tolerability between transdermal fentanyl and oral oxycodone in patients with cancer pain

UMIN ID: C000000339

Registered date:01/01/2007

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: Cancer pain
• Date of first enrollment: 2006/03/01
• Target sample size: 40
• Countries of recruitment: Japan
• Study type: Interventional
• Intervention(s): Oral oxycodone-transdermal fentanyl

Outcome(s)

• Primary Outcome: Evaluation of a conversion ratio of oral oxycodone to transdermal fentanyl
• Secondary Outcome: Comparison of side effects between oral oxycodone and transdermal fentanyl

Key inclusion & exclusion criteria

• Age minimum: Not applicable
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: (1) patients with severe hepatic, renal, cardiocascular or pulmonary disease (2) patients with past history of heart or psychiatric disease (3) preganat or nursing patients and patients who may be pregnant (4) unconsciousness patient who cannot communicate (5) Patients who have contraindication to oral oxycodone and transdermal fentanyl (6) Patients taking fentanyl, extended-release morphine or opioid agonist-antagonists (7) A daily dose of oxycodone is not constant after agreement (8) Patients with a medical problem with this study

Related Information

• Primary Sponsor: Department of anesthesia, Kyoto University Hospital
• Source(s) of Monetary Support: None