UMIN ID: C000000304
Registered date:11/01/2006
Randomized controlled trial of two intravenous doses of granisetron (1mg vs 3mg) for the prophylaxis of chemotherapy-induced nausea and vomiting in cancer patients
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | breast cancer , ovarian cancer , cervical cancer , endometrial cancer , etc |
| Date of first enrollment | 2006/01/01 |
| Target sample size | 180 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Granisetron 1mg/body (drip on intravenous,day1) Granisetron 3mg/body (drip on intravenous,day1) |
Outcome(s)
| Primary Outcome | Complete Response |
|---|---|
| Secondary Outcome | Complete control |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | (1)patients with known hypersensitivity to 5-HT3 receptor antagonist (2)patients to use the neoplastic agents belong to the acute emetic category intermediate and High risk or to do the radiation therapy between Day2 and 7 (3)serious complications excepting malignancy (e.g. bowel obdormition, fibroid lung, cerebrovascular accident, active gastric and duodenum) (4)can't exactly record episodes in diaries, Shoujyou-nisshi |
Related Information
| Primary Sponsor | Pharmacy Division of National Cancer Center Hospital |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Ministry of Health, Labour and Welfare |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Masahito Yonemura |
| Address | 5-1-1 Tsukiji,Chuuou-ku,Tokyo,104-0045,Japan Japan |
| Telephone | 03-3542-2511 |
| myonemur@ncc.go.jp | |
| Affiliation | Granisetorn coordinating office Pharmacy Division of National Cancer Center Hospital |
| scientific contact | |
| Name | Taisuke Hojo , Ph.D |
| Address | 5-1-1 Tsukiji,Chuuou-ku,Tokyo,104-0045,Japan Japan |
| Telephone | 03-3542-2511 |
| Affiliation | National Cancer Center Hospital Pharmacy Division |