A single blind, multi centered randomized control trial to investigate prevention effect of traditional Chinese herbal medicine Banxia Houpu Tang on the aspiration pneumonia in elderly.

UMIN ID: C000000277

Registered date:08/11/2005

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: Aspiration pneumonia
• Date of first enrollment: 2005/01/01
• Target sample size: 100
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Patients in active treatment group took 7.5g BHT extract each day, 3 times before meal, one year (from March 2005 to Feb. 2006). They also took all known conventional therapies including swallowing training, ACE inhibitors, and rehabilitation.
Patient in control group took conventional therapies same as above.

Outcome(s)

• Primary Outcome: Frequency of aspiration pneumonia, survival rate, amount of eating meals, whole ADL level, medical cost
• Secondary Outcome: Cognition

Key inclusion & exclusion criteria

• Age minimum: 65years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: Patients who have chronic lung diseases, malignancies, immunodeficiency i.e. HIV infection, who has severe liver disfunction, severe renal disfunction, ischemic heart diseases, Patients who took other Chinese herbal medicines. Patients who can not take BHT per os.

Related Information

• Primary Sponsor: Division of Geriatrics and Complementary medicine, Tohoku University, post graduate school of medicine
• Secondary Sponsor: Utsunomiya-Higashi Hospital
• Source(s) of Monetary Support: None