UMIN ID: C000000272
Registered date:15/11/2005
Genome-wide case-control association study to identify susceptibility gene to diabetic nephropathy using single nucleotide polymorphisms.
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | Diabetic nephropathy |
| Date of first enrollment | 2001/06/01 |
| Target sample size | 2000 |
| Countries of recruitment | Japan |
| Study type | Observational |
| Intervention(s) |
Outcome(s)
| Primary Outcome | Diabetic patients with diabetic retinopathy were divided into two groups: 1) nephropathy cases (DN):-patients with overt nephropathy, 2) controls (C):-patients showing no evidence of renal dysfunction (based on the urinary albumin levels). Our first screening involved genotyping 94 DNs and 94 Cs for 10,000 SNP loci, and we further analyzed the SNP loci showing significant differences in allelic frequencies between DN and C using a larger number of patients. |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | Not applicable |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Patients with other chronic renal diseases. |
Related Information
| Primary Sponsor | RIKEN |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | RIKEN |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Shiro Maeda |
| Address | 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan Japan |
| Telephone | 045-503-9595 |
| smaeda@src.riken.jp | |
| Affiliation | SNP Research Center, RIKEN Laboratory for Diabetic Nephropathy |
| scientific contact | |
| Name | Shiro Maeda |
| Address | 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan Japan |
| Telephone | 045-503-9595 |
| Affiliation | SNP Research Center, RIKEN Laboratory for Diabetic Nephropathy |