UMIN ID: C000000244
Registered date:22/09/2005
Phase II study of salvage photodynamic therapy for local failure after definitive chemoradiotherapy for patients with esophageal squamous cell carcinoma
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | esophageal squamous cell carcinoma |
| Date of first enrollment | 2005/02/01 |
| Target sample size | 37 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Photodynamic therapy |
Outcome(s)
| Primary Outcome | Complete response rate of primary site |
|---|---|
| Secondary Outcome | Occurence rate of adverse event Progression free survival Overall survival |
Key inclusion & exclusion criteria
| Age minimum | Not applicable |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1) No other active malignancy 2) No other severe medical conditions 3) Patients who are suffered systemic infection 4) Patients who cannot keep shading 5) Lesions were judged within mucosal laiyer, and can be treated with EMR 6) Lesions were assessed as T4 before CRT. 7) clinically defined distant or lymph node metastasis by computed tomography and endoscopic ultrasound (EUS) before PDT 8) Patients with porphyria 9) Lesions were not completely evaluated because of stenosis after CRT |
Related Information
| Primary Sponsor | National Cancer Center Hospital East |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Ministry of Health, Labour and Welfare |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Tomonori Yano |
| Address | Japan |
| Telephone | |
| toyano@east.ncc.go.jp | |
| Affiliation | National Cancer Center Hospital East Division of digestive endoscopy and GI oncology |
| scientific contact | |
| Name | Manabu Muto |
| Address | 6-5-1, Kashiwanoha, Kashiwa, Chiba, Japan Japan |
| Telephone | 04-7133-1111 |
| Affiliation | National Cancer Center Hospital East Division of digestive endoscopy and GI oncology |