A Randomized Clinical Trial of High-Dose Chemotherapy with Autologous Peripheral Blood Stem Cell Transplantation in Limited-Disease Small-Cell Lung Cancer.

UMIN ID: C000000214

Registered date:13/09/2005

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: Small-cell lung cacer, limited disease
• Date of first enrollment: 2001/07/01
• Target sample size: 90
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Cisplatin + etoposide with conccrent accelerated hyperfractionated thoracic radiation therapy followed by high-dose chemotherapy (ifosfamide/carboplatin/etoposide) with autologous peripheral blood stem cell transplantation
Cisplatin + etoposide with conccrent accelerated hyperfractionated thoracic radiation therapy

Outcome(s)

• Primary Outcome: 5-year disease free survival

Key inclusion & exclusion criteria

• Age minimum: Not applicable
• Age maximum: 65years-old
• Gender: Male and Female
• Exclude criteria: Patients who had tumors involvement in the bone marrow or brain, active double cancers or serious underlying disease (interstitial pneumonia, serious cardiac diseases, uncontrolled diabetes mellitus, serious infection, carrier of HBV, HCV,or HIV) are excluded.

Related Information

• Primary Sponsor: Japan SCLC/PBSCT Study Group
• Source(s) of Monetary Support: None