NIPH Clinical Trials Search

UMIN ID: C000000214

Registered date:13/09/2005

A Randomized Clinical Trial of High-Dose Chemotherapy with Autologous Peripheral Blood Stem Cell Transplantation in Limited-Disease Small-Cell Lung Cancer.

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedSmall-cell lung cacer, limited disease
Date of first enrollment2001/07/01
Target sample size90
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Cisplatin + etoposide with conccrent accelerated hyperfractionated thoracic radiation therapy followed by high-dose chemotherapy (ifosfamide/carboplatin/etoposide) with autologous peripheral blood stem cell transplantation Cisplatin + etoposide with conccrent accelerated hyperfractionated thoracic radiation therapy


Primary Outcome5-year disease free survival
Secondary Outcome

Key inclusion & exclusion criteria

Age minimumNot applicable
Age maximum65years-old
GenderMale and Female
Include criteria
Exclude criteriaPatients who had tumors involvement in the bone marrow or brain, active double cancers or serious underlying disease (interstitial pneumonia, serious cardiac diseases, uncontrolled diabetes mellitus, serious infection, carrier of HBV, HCV,or HIV) are excluded.

Related Information


public contact
Name Katsuyuki Kiura, M.D. Ph.D.
Address 2-5-1 Shikata-cho, Okayama700-8558 Japan
Telephone 086-235-7225
Affiliation Okayama University Graduate School of Medicine, Dentistry, and Phamaceutical Science Department of Hematology, Oncology, and Respiratory Midicine
scientific contact
Name Mine Harada, M.D, Ph.D. Professor & Chairman
Address 3-1-1Maidashi, Higashiku, Fukuoka Japan
Telephone 092-642-1151
Affiliation Kyushu University Faculty of Medical Sience