NIPH Clinical Trials Search

UMIN ID: C000000199

Registered date:13/09/2005

Therapeutic angiogenesis for peripheral artery diseases by combination of adrenomedullin and peripheral mononuclear cell transplantation

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedperipheral artery disease
Date of first enrollment2004/08/01
Target sample size6
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Transplantation of peripheral mononuclear cells into ischemic limb muscles, followed by administration of adrenomedullin.


Primary OutcomeAdverse events
Secondary OutcomeImprovement of pain, skin necrosis, and walking distance

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximumNot applicable
GenderMale and Female
Include criteria
Exclude criteria1)malignant disorder. 2)uncontrolled liver disorder. 3)acute myocardial infarction, unstable angina, myocarditis, cerebral infarction within one month. 4)active infection. 5)pregnancy or child bearing potentials. 6)diabetic retinopathy (untreated proliferative retinopathy).

Related Information


public contact
Name Satoshi Takeshita
Address Japan
Telephone 06-6833-5012
Affiliation National Cardiovascular Center Cardiology
scientific contact
Name Takeshi Nakatani
Address 5-7-1 Fujishiro-dai, Suita, Osaka Japan
Telephone 06-6833-5012
Affiliation National Cardiovascular Center Department of Organ Transplantation