UMIN ID: C000000199
Registered date:13/09/2005
Therapeutic angiogenesis for peripheral artery diseases by combination of adrenomedullin and peripheral mononuclear cell transplantation
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | peripheral artery disease |
| Date of first enrollment | 2004/08/01 |
| Target sample size | 6 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Transplantation of peripheral mononuclear cells into ischemic limb muscles, followed by administration of adrenomedullin. |
Outcome(s)
| Primary Outcome | Adverse events |
|---|---|
| Secondary Outcome | Improvement of pain, skin necrosis, and walking distance |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1)malignant disorder. 2)uncontrolled liver disorder. 3)acute myocardial infarction, unstable angina, myocarditis, cerebral infarction within one month. 4)active infection. 5)pregnancy or child bearing potentials. 6)diabetic retinopathy (untreated proliferative retinopathy). |
Related Information
| Primary Sponsor | National Cardiovascular Center |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Ministry of Health, Labour and Welfare |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Satoshi Takeshita |
| Address | Japan |
| Telephone | 06-6833-5012 |
| Affiliation | National Cardiovascular Center Cardiology |
| scientific contact | |
| Name | Takeshi Nakatani |
| Address | 5-7-1 Fujishiro-dai, Suita, Osaka Japan |
| Telephone | 06-6833-5012 |
| Affiliation | National Cardiovascular Center Department of Organ Transplantation |