UMIN ID: C000000119
Registered date:07/09/2005
Gene evaluation for antihypertensive drug effects study
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | essential hypertension |
| Date of first enrollment | 2004/04/01 |
| Target sample size | 300 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | thiazide diuretics indapamide calcium channel blocker amlodipine angiotensin II receptor blocker valsartan |
Outcome(s)
| Primary Outcome | gene polymorphisms relating to blood pressure lowering effect of thiazide diuretics, calcium channel blocker, angiotensin II receptor blocker |
|---|---|
| Secondary Outcome | gene polymorphisms relating to side effects of thiazide diuretics, calcium channel blocker, angiotensin II receptor blocker |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | severe hypertension (more than 180 and/or 110 mmHg) secondary hypertension female with pregnancy |
Related Information
| Primary Sponsor | National Cardiovascular Center |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Research grant from the Japanese Ministry of Health, Labor, and Welfare |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Kei Kamide |
| Address | 5-7-1, Fujishirodai, Suita, Osaka 565-8565 Japan |
| Telephone | 06-6833-5012 |
| kamide@hsp.ncvc.go.jp | |
| Affiliation | National Cardiovascular Center Division of Hypertension and Nephrology |
| scientific contact | |
| Name | Yuhei Kawano |
| Address | 5-7-1, Fujishirodai, Suita, Osaka 565-8565 Japan |
| Telephone | 06-6833-5012 |
| Affiliation | National Cardiovascular Center Division of Hypertension and Nephrology |