NIPH Clinical Trials Search

UMIN ID: C000000107

Registered date:01/09/2005

DIAbetes and diffuse coronary Narrowing Analysis Study

Basic Information

Recruitment status Complete: follow-up continuing
Health condition(s) or Problem(s) studiedPatients with impaired fasting glucose or type-2 diabetes mellitus, who had coronary artery diseases
Date of first enrollment2005/02/01
Target sample size300
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Patients treated with voglibose (n=100) Patients treated with nateglinide (n=100) patients treated without medication, with diet and exercise (n=100)


Primary OutcomeLesion length, vessel diameter, percentage diameter stenosis
Secondary OutcomeMACE (all-cause death, non-fatal myocardial infarction, repeat revascularization, the occurrence of anginal chest pain), diabetic complication, the change of % diameter stenosis after PCI, the change of minimum lesional diameter after PCI, the occurrence of restenosis, the development of new stenotic lesion, the change of glycemic status

Key inclusion & exclusion criteria

Age minimumNot applicable
Age maximumNot applicable
GenderMale and Female
Include criteria
Exclude criteria1) patinets with acute myocardial infarction within 48 hrs 2) patients who previously underwent coronary artery bypass surgery 3) patients who were being treated by anti-diabetic medication 4) patients who had allergic reaction to voglibose or nateglinide 5) patients with real insufficiency (serun creatinine more than 2.0mg/dl) 6) patients who were seriously ill

Related Information


public contact
Address Japan
Telephone 06-6833-5012
Affiliation National Cardiovascular Center The Division of Atheroscierosis, Metabolism and Clinical Nutrition
scientific contact
Name Shunichi Miyazaki
Address 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565, Japan Japan
Telephone 06-6833-5012
Affiliation National Cardiovascular Center Division of Cardiology