UMIN ID: C000000090
Registered date:31/08/2005
The Japan Working Group for the Assessment That the Alpha-glucosidase-inhibitor Blocks Cardiac Events in Patients With Myocardial Infarction and IGT
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Patients With Myocardial Infarction and IGT |
| Date of first enrollment | 2005/04/01 |
| Target sample size | 1570 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | In the voglibose group, voglibose will be prescribed at 0.6mg three times daily. In control group, each participated doctor will instruct patients on a weight reduction or weight maintenance diet, and encouraged them to exercise regularly. |
Outcome(s)
| Primary Outcome | 1.Cardiovascular mortality 2.Hospitalization due to cardiovascular events |
|---|---|
| Secondary Outcome | (1) All cause mortality (2) Hospitalization due to coronary artery disease (3) Progression of IGT to diabetes (4) Development or deterioration of either hypertension or hyperlipidemia (5) Deterioraion of renal function (6) Hospitalization due to cerebrovascular disease (7) Hospitalization due to heart failure |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 100years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1.Type I diabetes 2.History of coronary artery bypass graft 3.Severe liver and/or kidney dysfunction 4.History of allergic response to drugs 5.arteriosclerosis obliterans |
Related Information
| Primary Sponsor | National Cardiovascular Center |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Grants in Health and Labour Sciences Research from the Ministry of Health, Labour and Welfare, Japan. |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Masafumi Kitakaze |
| Address | 5-7-1 Fujishirodai, Suita Osaka 565-8565, JAPAN Japan |
| Telephone | 06-6836-5012 |
| kitakaze@zf6.so-net.ne.jp | |
| Affiliation | Clinical Study Support Center Japan (CSSCJ) ABC office |
| scientific contact | |
| Name | Masafumi Kitakaze |
| Address | 5-7-1 Fujishirodai, Suita City, Osaka Pref. 565-8565, Japan Japan |
| Telephone | 06-6833-5012 |
| kitakaze@zf6.so-net.ne.jp | |
| Affiliation | National Cardiovascular Center Cardiovascular Division |