NIPH Clinical Trials Search

UMIN ID: C000000053

Registered date:09/08/2005

CHOP therapy for low and low-intermediate risk patients of advanced aggressive non-Hodgkin's lymphoma (JCOG9508, LSG17(CHOP))

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedlow and low-intermediate risk of aggressive non-Hodgkin's lymphoma
Date of first enrollment1995/06/01
Target sample size160
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Chemotherapy (8 courses of CHOP)


Primary Outcomeoverall survival
Secondary OutcomeComplete remission rate, Progression free survaval, adverse reaction/adverse effect

Key inclusion & exclusion criteria

Age minimum15years-old
Age maximum70years-old
GenderMale and Female
Include criteria
Exclude criteria1) Complication; severe infection, heart failure, respiratory failure, hepatic failure, organic pulumonary disease, liver cirrhosis, acute or chronic hepatitis, renal failure. 2) Active or non-curable synchronous malignancy, except for cervical carcinoma in situ or basal carcinoma of the skin. 3) Psycological disorder like schizophrenia. 4) Heart disease which is deteriorated by anthracyclins, past history of myocardial infarction, or angina pectoris during 3 months before registration. 5) Pregnant or nursing . 6) Involvement of central nervous system 7) HIV infection

Related Information


public contact
Name Yoshitoyo Kagami, MD, PhD
Address 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, JAPAN Japan
Affiliation JCOG9508 Coordinating Office Department of Hematology and Cell-therapy, Aichi Cancer Center Hospital
scientific contact
Name Michinori Ogura, MD, PhD
Address 2-9 myouken-cho, Shouwa-ku, Nagoya, JAPAN Japan
Affiliation Nagoya Daini Red-cross Hospital Department of Hematology