NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
UMIN ID: C000000036

Registered date:04/08/2005

Randomized phase III study of Standard CHOP(S-CHOP) versus Biweekly CHOP(Bi-CHOP) in aggressive Non-Hodgkin's Lymphoma(JCOG9809)

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedNon-Hodgkin's lymphoma
Date of first enrollment1999/02/01
Target sample size450
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Chemotherapy:Standard CHOP Chemotherapy:Bi-CHOP(dose intensified CHOP)

Outcome(s)

Primary OutcomeProgression free survival
Secondary Outcomeoverall survival, complete remission rate, toxicity

Key inclusion & exclusion criteria

Age minimum15years-old
Age maximum69years-old
GenderMale and Female
Include criteria
Exclude criteria(1)uncontrolable diabetes mellitus (2)severe complication (infection, heart failure, renal failure, liver failure, etc) (3)anamnesis of heart disease (4)acute or chronic hepatitis, liver chirrosis and portal hypertension (5)synchronous or metachronous malignancy (6)sever plumonary dysfunction (7)CNS invasion (8)HIV positive (9)HBs-Ag positive (10)HCV-Ab positive

Related Information

Contact

public contact
Name Ken Ohmachi, MD
Address 143 Simolasuya, Isehara, Kanagawa, 259-1193, Japan Japan
Telephone
E-mail JCOG_sir@ml.jcog.jp
Affiliation JCOG9809 Coordinating Office Department of Medicine, Hematology/Oncology, Tokai university
scientific contact
Name Tomomitsu Hotta, MD, PhD
Address 143 Simolasuya, Isehara, Kanagawa, 259-1193, Japan Japan
Telephone
E-mail
Affiliation Tokai university Department of Medicine, Hematology/Oncology