Randamized clinical trial for effect of intraoperative auto blood donation for bleeding during liver resection in living liver transplantation

UMIN ID: C000000015

Registered date:23/08/2005

Basic Information

• Health condition(s) or Problem(s) studied: Living liver donor
• Date of first enrollment: 2003/12/01
• Target sample size: 80
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Participated patients will be divided into two groups randomaly. One is blood donotion group and the other is non-blood donoation group. Pstients in blood donation group will be donated auto blood which is equal to 0.7 % of their body weight at the begining of the operation. It will be tranptranted to them before the operation will be finished.
Patients in non-blood donoation group will not be added extra treatment or intervention.

Outcome(s)

• Primary Outcome: amount of bleeding during hepatic resection
• Secondary Outcome: total amount of bleeding in operation, time of hepatic resectioon, duration of hospital stay.

Key inclusion & exclusion criteria

• Age minimum: 18years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: 1) Patients with hypertension or hypotension 2) Patients with remarkable abnormal anatomy of the liver 3) patients with anemia (Hb<11g/dl) 4) Patients with comorbidity 5) Patients with tendency of bleeding 6) Patients who would not achieve stable circulation condition during operation

Related Information

• Primary Sponsor: University of Tokyo,Department of Surgery, Hepato-Biliary-Pancreatic Surgery Division, Artificial Organ and Transplantatation
• Source(s) of Monetary Support: no