NIPH Clinical Trials Search

UMIN ID: C000000004

Registered date:07/06/2005

Randomized Controlled Trial to Evaluate Splenectomy in Total Gastrectomy for Proximal Gastric Carcinoma(JCOG0110, GCSSG-SPNX)

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedT2, T3, and T4 carcinoma in the proximal third of the stomach
Date of first enrollment2002/06/01
Target sample size500
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)A:Surgery:splenectomy B:Surgery:spleen-preservation


Primary Outcomeoverall survival
Secondary Outcomerelapse-free survival, post-operative morbidity, operation time and perioperative blood loss

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximum75years-old
GenderMale and Female
Include criteria
Exclude criteria(1) Liver cirrhosis or portal hypertension (2) idiopathic thrombocytopenic purpura (3) severe pulmonary dysfunction (4)synchronous or metachronous (within 5 years) malignancy

Related Information


public contact
Name Takeshi Sano, MD, PhD
Address 3-10-6, Ariake, Koto-ku, Tokyo, 135-8550, JAPAN Japan
Telephone 03-3520-0111
Affiliation JCOG0110 Coordinating Office Gastroenterological Surgery, Cancer Institute Hospital
scientific contact
Name Mitsuru Sasako, MD, PhD
Address 1-1 Mukogawacho, Nishinomiya, Hyogo, Japan Japan
Telephone 0798-45-6767
Affiliation Hyogo College of Medicine Upper GI Surgery Division