NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
JRCT ID: jRCTs072220028

Registered date:25/07/2022

Development of treatments for movement disorders by brain stimulation.

Basic Information

Recruitment status Recruiting
Health condition(s) or Problem(s) studiedcentral nervous system dysorders
Date of first enrollment26/09/2022
Target sample size30
Countries of recruitment
Study typeInterventional
Intervention(s)Methods of brain stimulation (1) rTMS: The motor cortex on the disordered side is stimulated at 5 Hz, subthreshold stimulation intensity, 10 s stimulation, 50 s rest for 10 min. (2) Double-shot TMS: The motor cortex on the affected side is stimulated 200 times at 1.5 ms intervals in double-shot at suprathreshold stimulation intensity. (3) tDCS: The impaired motor cortex is stimulated as anode and the unaffected motor cortex as cathode at a stimulation intensity of 2 mA for 20 min. One of (1), (2) or (3) should be performed. After one of (1), (2) or (3) is performed, regular upper limb rehabilitation (20-60 min) is performed within 1 h. After the second session, one of (1), (2) or (3) and upper limb rehabilitation are performed in the same way. 9 treatment interventions (5 days a week, 13 days a week) are performed.

Outcome(s)

Primary OutcomeFugl Meyer Assessment, Assessment of visuomotor tasks
Secondary OutcomeAction Research Arm Test, Box and Block Test, Assessment of drawing tasks

Key inclusion & exclusion criteria

Age minimum>= 20age old
Age maximum<= 80age old
GenderBoth
Include criteriaMovement disorders due to central nervous system disorders
Exclude criteriaPatients with cardiac pacemakers, implantable defibrillators or implantable neurostimulators.

Related Information

Contact

Public contact
Name Seiji Etoh
Address Sakuragaoka 8-35-1, Kagoshima-City, Kagoshima, Japan Kagoshima Japan 890-8520
Telephone +81-99-275-5339
E-mail etohs@m2.kufm.kagoshima-u.ac.jp
Affiliation Kagoshima University Graduate School
Scientific contact
Name Seiji Etoh
Address Sakuragaoka 8-35-1, Kagoshima-City, Kagoshima, Japan Kagoshima Japan 890-8520
Telephone +81-99-275-5339
E-mail etohs@m2.kufm.kagoshima-u.ac.jp
Affiliation Kagoshima University Graduate School