JRCT ID: jRCTs072220028
Registered date:25/07/2022
Development of treatments for movement disorders by brain stimulation.
Basic Information
Recruitment status | Recruiting |
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Health condition(s) or Problem(s) studied | central nervous system dysorders |
Date of first enrollment | 26/09/2022 |
Target sample size | 30 |
Countries of recruitment | |
Study type | Interventional |
Intervention(s) | Methods of brain stimulation (1) rTMS: The motor cortex on the disordered side is stimulated at 5 Hz, subthreshold stimulation intensity, 10 s stimulation, 50 s rest for 10 min. (2) Double-shot TMS: The motor cortex on the affected side is stimulated 200 times at 1.5 ms intervals in double-shot at suprathreshold stimulation intensity. (3) tDCS: The impaired motor cortex is stimulated as anode and the unaffected motor cortex as cathode at a stimulation intensity of 2 mA for 20 min. One of (1), (2) or (3) should be performed. After one of (1), (2) or (3) is performed, regular upper limb rehabilitation (20-60 min) is performed within 1 h. After the second session, one of (1), (2) or (3) and upper limb rehabilitation are performed in the same way. 9 treatment interventions (5 days a week, 13 days a week) are performed. |
Outcome(s)
Primary Outcome | Fugl Meyer Assessment, Assessment of visuomotor tasks |
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Secondary Outcome | Action Research Arm Test, Box and Block Test, Assessment of drawing tasks |
Key inclusion & exclusion criteria
Age minimum | >= 20age old |
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Age maximum | <= 80age old |
Gender | Both |
Include criteria | Movement disorders due to central nervous system disorders |
Exclude criteria | Patients with cardiac pacemakers, implantable defibrillators or implantable neurostimulators. |
Related Information
Primary Sponsor | Etoh Seiji |
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Secondary Sponsor | |
Source(s) of Monetary Support | |
Secondary ID(s) |
Contact
Public contact | |
Name | Seiji Etoh |
Address | Sakuragaoka 8-35-1, Kagoshima-City, Kagoshima, Japan Kagoshima Japan 890-8520 |
Telephone | +81-99-275-5339 |
etohs@m2.kufm.kagoshima-u.ac.jp | |
Affiliation | Kagoshima University Graduate School |
Scientific contact | |
Name | Seiji Etoh |
Address | Sakuragaoka 8-35-1, Kagoshima-City, Kagoshima, Japan Kagoshima Japan 890-8520 |
Telephone | +81-99-275-5339 |
etohs@m2.kufm.kagoshima-u.ac.jp | |
Affiliation | Kagoshima University Graduate School |