NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
JRCT ID: jRCTs061200045

Registered date:15/01/2021

The study for the moisturizing effect by trehalose(SMET)

Basic Information

Recruitment status Complete
Health condition(s) or Problem(s) studiednormal skin
Date of first enrollment15/01/2021
Target sample size40
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)People having the normal skin surfaces of the external aspects of the forearms and of the external aspects of the lower legs are used. Apply the left side studying cream on the external aspects of the left forearms and on the external aspects of the left lower legs two times a day. Apply the right side studying cream on the external aspects of the right forearms and on the external aspects of the right lower legs two times a day. Measure the water content of the corneum of every forearms and every lower legs on the starting day, after one week, after two weeks, after three weeks and after four weeks. The actual drug is the 0.3% heparinoid cream adding 5% trehalose. The placebo drug is the 0.3% heparinoid cream.

Outcome(s)

Primary OutcomeThe value of ASA-M3/R is correlated to the water content of the stratum corneum significantly.
Secondary OutcomeObserve the subjective and objective differences between pre-treatment and after-treatment.

Key inclusion & exclusion criteria

Age minimum>= 20age old
Age maximumNot applicable
GenderBoth
Include criteriaOn the external aspects of the forearms and the l ower legs of adults having the normal skin surface
Exclude criteriaPeople having the inflammatory skin diseases for example the atopic dermatitis,etc. and the hereditary skin diseases for example the ichthyosis, etc..

Related Information

Contact

Public contact
Name Haruyoshi Yamada
Address 3-1-21 Nishikatakura Hachiouji-shi Tokyo, Japan Tokyo Japan 192-0917
Telephone +81-42-635-2551
E-mail y-haru@msd.biglobe.ne.jp
Affiliation Yamada dermatological clinic
Scientific contact
Name Haruyoshi Yamada
Address 3-1-21 Nishikatakura Hachiouji-shi Tokyo, Japan Tokyo Japan 192-0917
Telephone +81-42-635-2551
E-mail y-haru@msd.biglobe.ne.jp
Affiliation Yamada dermatological clinic