Tear meniscus height after stimulated Menthol and comparison of lacrimation ability with Schirmer's test

JRCT ID: jRCTs061190033

Registered date:12/02/2020

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Dry eye
• Date of first enrollment: 03/07/2020
• Target sample size: 60
• Study type: Interventional
• Intervention(s): L-menthol was instilled, and the tear meniscus height before, after 1, 2, 3, 4, 5 minutes after the instillation was measured by AS-OCT, and compare with Schirmer's test.

Outcome(s)

• Primary Outcome: Stimulation of tear fluid height measurement after instillation of l-menthol by AS-OCT Utility as a lacrim secretory function test
• Secondary Outcome: Correlation between tear meniscus height measurement and Schirmer's test after l-menthol instillation by AS-OCT

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

Normal Volunteers 30 people, Dry eye patients 30 people
criteria: 1. Over 20 years old, 2. Written informed consent

• Exclude criteria: 1. Not written informed consent, 2. Inflammatory eye disease, 3. Using Punctal plug as a treatment for Dry eye or Dacryo Lacrimal Disease

Related Information

• Primary Sponsor: Shiraishi Atsushi