Effects of Highly Absorptive Curcumin (curcured) on knee osteoarthritis for three months

JRCT ID: jRCTs051200058

Registered date:24/09/2020

Basic Information

• Recruitment status: Complete
• Health condition(s) or Problem(s) studied: knee osteoarthritis
• Date of first enrollment: 24/09/2020
• Target sample size: 90
• Study type: Interventional
• Intervention(s): Highly Absorptive Curcumin (curcured) on knee osteoarthritis for three months

Outcome(s)

• Primary Outcome: JKOM, VAS, JOA knee OA score, dependence of NSAIDs
• Secondary Outcome: Time up and go, knee range of motion biochemical analysis of blood, blood concentration of curcumin

Key inclusion & exclusion criteria

• Age minimum: >= 40age old
• Age maximum: Not applicable
• Gender: Both
• Include criteria: 1)Medial knee osteoarthritis and KL classification II or III, 2) over 40 years. 3) consent of patient , 4) outpatient
• Exclude criteria: 1)Severe renal dysfunction or dialysis 2)severe liver dysfunction or liver cirrhosis 3)severe cardiovascular diseases 4)severe cerebrovascular dysfunction 5)severe diabetes mellitus 6)curcumin abuse patients 7)previous knee surgery or intraarticular injection for experimental period or steroid intraarticular injection before 2 months or steroid oral intake before 4 weeks 8)patient who must be excluded by the scientific responsible doctor

Related Information

• Primary Sponsor: Yamada Shigeru
• Secondary Sponsor: Therabiopharma